(R)-(+)-8-Hydroxy-DPAT hydrobromide

• CAT Number: I010366
• CAS Number: 78095-19-9
• Molecular Formula: C16H26BrNO
• Molecular Weight: 328.29
• Purity: ≥95%
• Synonyms: (2R)-(+)-8-Hydroxy-2-(di-n-propylamino)tetralin hydrobromide
• Solubility: Soluble to 75 mM in water and to 75 mM in DMSO
• Storage: Desiccate at +4°C
• IUPAC Name: (7R)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol;hydrobromide
• InChI: InChI=1S/C16H25NO.BrH/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14;/h5-7,14,18H,3-4,8-12H2,1-2H3;1H/t14-;/m1./s1
• InChIKey: BATPBOZTBNNDLN-PFEQFJNWSA-N
• SMILES: CCCN(CCC)C1CCC2=C(C1)C(=CC=C2)O.Br

(R)-(+)-8-Hydroxy-DPAT hydrobromide (Cat No.: I010366) is a selective agonist of the 5-HT1A receptor, a subtype of serotonin receptor involved in mood regulation, anxiety, and thermoregulation. Widely used in neuropharmacological research, it helps investigate serotonergic signaling and the role of 5-HT1A receptors in depression, anxiety disorders, and schizophrenia. The (R)-(+)-enantiomer is the active form, offering high affinity and specificity. The hydrobromide salt improves its solubility and stability for experimental use in vitro and in vivo, making it a valuable tool in CNS research.