(R)-9-Hydroxy Risperidone

• CAT Number: R047780
• CAS Number: 130049-85-3
• Molecular Formula: C23H27FN4O3
• Molecular Weight: 426.492
• Purity: ≥95%
• Synonyms: (9R)-3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro?-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one; (+)-9-Hydroxyrisperidone; 9-(R)-Paliperidone
• Storage: -20°C
• IUPAC Name: (9R)-3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
• InChI: InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3/t19-/m1/s1
• InChIKey: PMXMIIMHBWHSKN-LJQANCHMSA-N
• SMILES: CC1=C(C(=O)N2CCCC(C2=N1)O)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F

(R)-9-Hydroxy risperidone is the active metabolite of risperidone, an antipsychotic medication used to treat schizophrenia, bipolar disorder, and irritability in autism. This chiral compound contributes significantly to risperidone’s therapeutic effects by blocking dopamine and serotonin receptors in the brain. Research on (R)-9-hydroxy risperidone focuses on its pharmacokinetics, efficacy, and safety profile, aiming to optimize its use in psychiatric treatment and understand its role in managing symptoms of mental health disorders.