For research use only. Not for therapeutic Use.
Arundic Acidis is an astrocyte modulating agent, in acute ischemic stroke. It is a therapeutic agent for the treatment of neurodegenerative diseases including Alzheimer’s disease and Parkinson’s disease.
| Catalog Number | R013587 |
| CAS Number | 185517-21-9 |
| Synonyms | (2R)-2-Propyloctanoic Acid; (2R)-2-Propyloctanoic Acid; (R)-(-)-2-Propyloctanoic Acid; Arundic Acid; Cereact; ONO 2506; ONO 2506PO; Proglia; |
| Molecular Formula | C11H22O2 |
| Purity | ≥95% |
| Target | Neuronal Metabolism |
| Solubility | Soluble in DMSO > 10 mM |
| Storage | Store at +4C |
| IUPAC Name | (2R)-2-propyloctanoic acid |
| InChI | InChI=1S/C11H22O2/c1-3-5-6-7-9-10(8-4-2)11(12)13/h10H,3-9H2,1-2H3,(H,12,13)/t10-/m1/s1 |
| InChIKey | YCYMCMYLORLIJX-SNVBAGLBSA-N |
| SMILES | CCCCCCC(CCC)C(=O)O |
| Reference | </br>1:Improvement of some physicochemical properties of arundic acid, (R)-(-)-2-propyloctanonic acid, by complexation with hydrophilic cyclodextrins. Miyamoto Y, Nakahara M, Motoyama K, Ishiguro T, Oda Y, Yamanoi T, Okamoto I, Yagi A, Nishimura H, Hirayama F, Uekama K, Arima H.Int J Pharm. 2011 Jul 15;413(1-2):63-72. doi: 10.1016/j.ijpharm.2011.04.022. Epub 2011 Apr 21. PMID: 21540089 </br>2:Effect of arundic acid on serum S-100beta in ischemic stroke. Pettigrew LC, Kasner SE, Gorman M, Atkinson RP, Funakoshi Y, Ishibashi H; Arundic Acid (ONO-2506) Stroke Study Group..J Neurol Sci. 2006 Dec 21;251(1-2):57-61. Epub 2006 Nov 7. PMID: 17092520 </br>3:Arundic acid (ONO-2506) ameliorates delayed ischemic brain damage by preventing astrocytic overproduction of S100B. Asano T, Mori T, Shimoda T, Shinagawa R, Satoh S, Yada N, Katsumata S, Matsuda S, Kagamiishi Y, Tateishi N.Curr Drug Targets CNS Neurol Disord. 2005 Apr;4(2):127-42. Review. PMID: 15857298 |
