(R)-Baclofen hydrochloride

• CAT Number: I004405
• CAS Number: 63701-55-3
• Molecular Formula: C10H13Cl2NO2
• Molecular Weight: 250.12
• Purity: ≥95%
• Synonyms: (3R)-4-amino-3-(4-chlorophenyl)butanoic acid;hydrochloride
• Target: Neuronal Signaling
• Solubility: 10 mM in DMSO
• Storage: Store at -20C
• InChI: InChI=1S/C10H12ClNO2.ClH/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14;/h1-4,8H,5-6,12H2,(H,13,14);1H/t8-;/m0./s1
• InChIKey: WMNUVYYLMCMHLU-QRPNPIFTSA-N
• SMILES: C1=CC(=CC=C1[C@@H](CC(=O)O)CN)Cl.Cl

(R)-Baclofen Hydrochloride(CAT: I004405) is the active enantiomer of baclofen, a selective GABA_B​ receptor agonist widely used in neuroscience and pharmacology research. It is known for its ability to modulate neurotransmission by inhibiting presynaptic calcium influx, reducing excitatory neurotransmitter release. This compound plays a key role in studies of spasticity, neuropathic pain, and addiction due to its muscle relaxant and anti-craving properties. The high purity of (R)-Baclofen Hydrochloride ensures reliable results in both in vitro and in vivo experimental setups, making it a critical tool for exploring therapeutic approaches targeting central nervous system disorders.