(R)-Betaxolol-d7 Hydrochloride

• CAT Number: R058658
• CAS Number: NA
• Molecular Formula: C₁₈H₂₃D₇ClNO₃
• Molecular Weight: 350.93
• Purity: ≥95%
• Synonyms: (2R)-1-[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl-d7)amino]-2-propanolHydrochloride; (+)-Betaxolol-d7 Hydrochloride; (R)-(+)-Betaxolol-d7 Hydrochloride; Dextrobetaxolol-d7 Hydrochloride
• Storage: -20°C
• IUPAC Name: (2R)-1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(1,1,1,2,3,3,3-heptadeuteriopropan-2-ylamino)propan-2-ol;hydrochloride
• InChI: InChI=1S/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16;/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3;1H/t17-;/m1./s1/i1D3,2D3,14D
• InChIKey: CHDPSNLJFOQTRK-CFDMMCIXSA-N
• SMILES: [2H]C([2H])([2H])C([2H])(C([2H])([2H])[2H])NC[C@H](COC1=CC=C(C=C1)CCOCC2CC2)O.Cl

(R)-Betaxolol-d7 Hydrochloride is a deuterated form of (R)-betaxolol, a selective beta-1 adrenergic receptor blocker used primarily in the treatment of glaucoma and hypertension. This compound is labeled with seven deuterium atoms, enhancing its stability and making it particularly useful in pharmacokinetic studies, drug metabolism research, and isotope-dilution mass spectrometry. The hydrochloride salt form ensures good solubility in aqueous solutions, making it ideal for biological assays. (R)-Betaxolol-d7 Hydrochloride is essential for investigating the ADME (absorption, distribution, metabolism, and excretion) properties of betaxolol in biological systems. It serves as a reliable internal standard in analytical chemistry, providing precise and reproducible results in pharmaceutical research, particularly in the development and optimization of cardiovascular therapies.