(R)-Bicalutamide

• CAT Number: R002661
• CAS Number: 113299-40-4
• Molecular Formula: C18H14F4N2O4S
• Molecular Weight: 430.37
• Purity: ≥95%
• Synonyms: (2R)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide; (R)-Casodex
• Target: Androgen Receptor
• Storage: Store at +4°C
• IUPAC Name: (2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methylpropanamide
• InChI: InChI=1S/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25)/t17-/m0/s1
• InChIKey: LKJPYSCBVHEWIU-KRWDZBQOSA-N
• SMILES: CC(CS(=O)(=O)C1=CC=C(C=C1)F)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O

(R)-Bicalutamide（Cat No.:R002661） is the enantiomer of bicalutamide, a medication used in the treatment of prostate cancer. Unlike its (S)-enantiomer, (R)-bicalutamide does not possess antiandrogenic activity and does not competitively inhibit the action of androgens at the androgen receptor. Therefore, (R)-bicalutamide is not used for its antiandrogenic effects in the treatment of prostate cancer. However, (R)-bicalutamide may have other potential uses or effects that are distinct from those of (S)-bicalutamide and further research is needed to explore these possibilities.