For research use only. Not for therapeutic Use.
Less active opposite R-(-)-enantiomer of S-(+)-enantiomer, BMS-204352 (Flindokalner, Axon 1112), a Maxi-K channel opener
| Catalog Number | I047521 |
| CAS Number | 187523-36-0 |
| Molecular Formula | C16H10ClF4NO2 |
| Purity | ≥95% |
| IUPAC Name | (3R)-3-(5-chloro-2-methoxyphenyl)-3-fluoro-6-(trifluoromethyl)-1H-indol-2-one |
| InChI | InChI=1S/C16H10ClF4NO2/c1-24-13-5-3-9(17)7-11(13)15(18)10-4-2-8(16(19,20)21)6-12(10)22-14(15)23/h2-7H,1H3,(H,22,23)/t15-/m1/s1 |
| SMILES | COC1=C(C=C(C=C1)Cl)[C@@]2(C3=C(C=C(C=C3)C(F)(F)F)NC2=O)F |
| Reference | Krishna R et al. Pharmacokinetics and dose proportionality of BMS-204352 after intraarterial administration to rats. Biopharm Drug Dispos. 2002, 23(6), 233-7.
M. P. G. Korsgaard et al. Anxiolytic Effects of Maxipost (BMS-204352) and Retigabine via Activation of Neuronal Kv7 Channels. J. Pharmacol. Exp. Ther. 2005, 314, 282-292. |
