(R)-Carprofen

• CAT Number: R050572
• CAS Number: 52263-83-9
• Molecular Formula: C15H12ClNO2
• Molecular Weight: 273.716
• Purity: ≥95%
• Synonyms: (αR)-6-Chloro-α-methyl-9H-carbazole-2-acetic Acid; (-)-Carprofen; (R)-(-)-Carprofen; ; C 8011
• Storage: -20°C
• IUPAC Name: (2R)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid
• InChI: InChI=1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)/t8-/m1/s1
• InChIKey: PUXBGTOOZJQSKH-MRVPVSSYSA-N
• SMILES: CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)O

(R)-Carprofen is the enantiomer of the nonsteroidal anti-inflammatory drug (NSAID) carprofen, widely used for its analgesic, anti-inflammatory, and antipyretic properties. While the (S)-enantiomer is primarily responsible for inhibiting cyclooxygenase (COX) enzymes and reducing inflammation, (R)-Carprofen has been studied for its different pharmacological effects, including its potential role in neuroprotection and lower toxicity profiles. (R)-Carprofen is less commonly used in therapeutic contexts compared to its racemic mixture or the (S)-form, but it remains an area of interest for understanding the stereoselective actions of NSAIDs in pain management and inflammation control.