(R)-(+)-Celiprolol-d9 Hydrochloride

• CAT Number: R049902
• CAS Number: 1330045-90-3
• Molecular Formula: C20H34ClN3O4
• Molecular Weight: 425.014
• Purity: ≥95%
• Synonyms: N’-[3-Acetyl-4-[(2R)-3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl]-N,N-diethylurea-d9 Hydrochloride; (+)-(R)-Celiprolol-d9 Hydrochloride; (+)-Celiprolol-d9 Hydrochloride; (R)-Celiprolol-d9 Hydrochloride; d-Celiprolol-d9 Hydrochloride
• Storage: -20°C
• IUPAC Name: 3-[3-acetyl-4-[(2R)-3-[[1,1,1,3,3,3-hexadeuterio-2-(trideuteriomethyl)propan-2-yl]amino]-2-hydroxypropoxy]phenyl]-1,1-diethylurea;hydrochloride
• InChI: InChI=1S/C20H33N3O4.ClH/c1-7-23(8-2)19(26)22-15-9-10-18(17(11-15)14(3)24)27-13-16(25)12-21-20(4,5)6;/h9-11,16,21,25H,7-8,12-13H2,1-6H3,(H,22,26);1H/t16-;/m1./s1/i4D3,5D3,6D3
• InChIKey: VKJHTUVLJYWAEY-ZRKVMCHMSA-N
• SMILES: [2H]C([2H])([2H])C(C([2H])([2H])[2H])(C([2H])([2H])[2H])NC[C@H](COC1=C(C=C(C=C1)NC(=O)N(CC)CC)C(=O)C)O.Cl

(R)-(+)-Celiprolol-d9 Hydrochloride is a deuterated form of Celiprolol, specifically labeled with nine deuterium atoms. This high-purity isotopically labeled compound is essential for research in cardiovascular pharmacology, particularly in the study of β1-selective adrenergic blockers used for treating hypertension and other heart conditions. It is widely used in mass spectrometry and other analytical techniques to explore the pharmacokinetics, metabolism, and therapeutic effects of Celiprolol in biological systems. The deuterium labeling provides enhanced precision and reliability in analytical measurements, making (R)-(+)-Celiprolol-d9 Hydrochloride a valuable tool for researchers focused on developing and optimizing cardiovascular therapies.