(R)-DOI hydrochloride

• CAT Number: I035465
• CAS Number: 82864-02-6
• Molecular Formula: C22H34Cl2I2N2O4
• Molecular Weight: 715.2329
• Purity: 98%
• Synonyms: (R)-DOI hydrochloride
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: (-)-2,5-Dimethoxy-4-iodoamphetamine hydrochloride; (2R)-1-(4-Iodo-2,5-dimethoxyphenyl)propan-2-amine hydrochloride
• InChI: InChI=1S/2C11H16INO2.2ClH/c2*1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2;;/h2*5-7H,4,13H2,1-3H3;2*1H/t7-;;;/m1.../s1
• InChIKey: PUBKQKMSEVIWPV-LSBIWMFESA-N
• SMILES: NC(CC1=CC(OC)=C(I)C=C1OC)C.[H]Cl.C[C@@H](N)CC2=CC(OC)=C(I)C=C2OC.[H]Cl

(R)-DOI hydrochloride is a 5-HT2 receptor agonist, inhibiting TNF-α-mediated proinflammatory signaling cascades and inflammation via 5-HT2A receptor activation and preventing the development of, and inflammation associated with, acute allergic asthma.