For research use only. Not for therapeutic Use.
(R)-Donepezil(CAT: I026443) is an enantiomer of the well-known acetylcholinesterase inhibitor donepezil, selectively enhancing cholinergic neurotransmission by inhibiting the breakdown of acetylcholine. With its enhanced potency in inhibiting acetylcholinesterase, (R)-Donepezil has shown promise in improving cognitive function and mitigating symptoms of Alzheimer’s disease in preclinical models. This compound’s specificity and efficacy in modulating cholinergic systems make it a valuable tool in Neurological Disease Research, particularly for advancing therapeutic strategies for neurodegenerative diseases such as Alzheimer’s.
| CAS Number | 142698-19-9 |
| Synonyms | (2R)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one |
| Molecular Formula | C24H29NO3 |
| Purity | ≥95% |
| IUPAC Name | (2R)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one |
| InChI | InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3/t20-/m1/s1 |
| InChIKey | ADEBPBSSDYVVLD-HXUWFJFHSA-N |
| SMILES | COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC |
