For research use only. Not for therapeutic Use.
(R)-Funapide ((R)-TV 45070) is the less active R-enantiomer of Funapide. Funapide is a potent Nav1.7 sodium channel blocker that can be used for pain research[1].
| Catalog Number | I045065 |
| CAS Number | 1259933-15-7 |
| Synonyms | (7R)-1′-[[5-(trifluoromethyl)furan-2-yl]methyl]spiro[6H-furo[2,3-f][1,3]benzodioxole-7,3′-indole]-2′-one |
| Molecular Formula | C22H14F3NO5 |
| Purity | ≥95% |
| InChI | InChI=1S/C22H14F3NO5/c23-22(24,25)19-6-5-12(31-19)9-26-15-4-2-1-3-13(15)21(20(26)27)10-28-16-8-18-17(7-14(16)21)29-11-30-18/h1-8H,9-11H2/t21-/m1/s1 |
| InChIKey | NEBUOXBYNAHKFV-OAQYLSRUSA-N |
| SMILES | C1C2(C3=CC=CC=C3N(C2=O)CC4=CC=C(O4)C(F)(F)F)C5=CC6=C(C=C5O1)OCO6 |
| Reference | [1]. Sharan K Bagal, et al. Recent progress in sodium channel modulators for pain. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3690-9. |
