For research use only. Not for therapeutic Use.
R-<wbr></wbr>1 methanandamide is the most potent CB<sub>1</sub> receptor agonist in the methanandamide series. It has a K<sub>i</sub> value of 20 nM for the CB<sub>1</sub> receptor, which is four-<wbr></wbr>fold lower than that of arachidonoyl ethanolamide (AEA) (K<sub>i</sub> =78 nM). In addition, R-<wbr></wbr>1 methanandamide is more resistant than AEA to hydrolytic inactivation by fatty acid amide hydrolase. The K<sub>i</sub> value for binding to the CB<sub>2</sub> receptor from mouse spleen is 815 nM.
| Catalog Number | R036569 |
| CAS Number | 157182-49-5 |
| Synonyms | [R-(all-Z)]-N-(2-Hydroxy-1-methylethyl)-5,8,11,14-eicosatetraenamide; ?(5Z,8Z,11Z,14Z)-N-[(1R)-2-Hydroxy-1-methylethyl]-5,8,11,14-eicosatetraenamide; AM 356 |
| Molecular Formula | C23H39NO2 |
| Purity | ≥95% |
| Storage | -20°C |
| InChIKey | SQKRUBZPTNJQEM-FQPARAGTSA-N |
