(R)-(+)-Nor Verapamil Hydrochloride

• CAT Number: C000295
• CAS Number: 147158-71-2
• Molecular Formula: C₂₆H₃₇ClN₂O₄
• Molecular Weight: 477.04
• Purity: ≥95%
• Synonyms: (αR)-α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-benzeneacetonitrile Hydrochloride; (R)-Norverapamil Hydrochloride
• Solubility: Chloroform (Slightly), Methanol (Very Slightly)
• Appearance: White to Light Brown Solid
• Storage: -20°C, Hygroscopic

(R)-(+)-Nor Verapamil Hydrochloride(CAT: C000295) holds significance in pharmaceutical chemistry. It is a stereoisomer of verapamil, a calcium channel blocker used to treat conditions like high blood pressure and angina. The (R)-(+)-Nor Verapamil Hydrochloride isomer may possess distinct pharmacological properties compared to the racemic mixture. Understanding the impact of stereochemistry on drug efficacy underscores its relevance in the field of drug development and design.

Reference

Mutlib, A.E., et al.: The Journal of Pharm. & Exp. Therapeutics, 252, 2, 593 (1989)