(R)-Ofloxacin

• CAT Number: R052215
• CAS Number: 100986-86-5
• Molecular Formula: C18H20FN3O4
• Molecular Weight: 361.37
• Purity: ≥95%
• Synonyms: (3R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid; (+)-Ofloxacin; (R)-(+)-Ofloxacin; D-Ofloxacin; DR 3354; d-Levofloxacin; Dextrofloxacin
• Storage: Room temperature
• IUPAC Name: (2R)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
• InChI: InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m1/s1
• InChIKey: GSDSWSVVBLHKDQ-SNVBAGLBSA-N
• SMILES: C[C@@H]1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O

(R)-Ofloxacin（Cat No.:R052215）, also known as levofloxacin, is the active enantiomer of the racemic mixture of ofloxacin, a fluoroquinolone antibiotic with broad-spectrum activity against both Gram-positive and Gram-negative bacteria. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and cell division, leading to bacterial cell death. (R)-Ofloxacin is commonly used to treat respiratory tract infections, urinary tract infections, and skin infections. Its high oral bioavailability, once-daily dosing, and strong antibacterial efficacy make it a preferred choice in clinical settings, especially for serious infections.