For research use only. Not for therapeutic Use.
(R)-Olacaftor ((R)-VX-440) is a Cystic fibrosis transmembrane conductance regulator (CFTR) modulator. (R)-Olacaftor has good potential for the study of cystic fibrosis (CF)[1].
| Catalog Number | I042674 |
| CAS Number | 1899111-41-1 |
| Synonyms | N-(benzenesulfonyl)-6-[3-fluoro-5-(2-methylpropoxy)phenyl]-2-[(4R)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide |
| Molecular Formula | C29H34FN3O4S |
| Purity | ≥95% |
| InChI | InChI=1S/C29H34FN3O4S/c1-19(2)18-37-23-14-21(13-22(30)15-23)26-12-11-25(27(31-26)33-17-20(3)16-29(33,4)5)28(34)32-38(35,36)24-9-7-6-8-10-24/h6-15,19-20H,16-18H2,1-5H3,(H,32,34)/t20-/m1/s1 |
| InChIKey | NHOUNZMCSIHKHJ-HXUWFJFHSA-N |
| SMILES | CC1CC(N(C1)C2=C(C=CC(=N2)C3=CC(=CC(=C3)F)OCC(C)C)C(=O)NS(=O)(=O)C4=CC=CC=C4)(C)C |
| Reference | [1]. Mark Thomas Miller, et al. Modulators of Cystic Fibrosis Transmembrane Conductance Regulator. Patent US20160095858A1. |
