For research use only. Not for therapeutic Use.
(R)-TCO-OH (Cat.No:I016603) is a chemical compound known as (R)-trans-cyclooctene-1-carboxylic acid. It is used in bioconjugation reactions, particularly in the strain-promoted azide-alkyne cycloaddition (SPAAC) reaction, also known as click chemistry. (R)-TCO-OH is valuable in preparing bioorthogonal linkers and conjugating biomolecules for various research and biomedical applications.
Catalog Number | I016603 |
CAS Number | 39637-78-0 |
Molecular Formula | C₈H₁₄O |
Purity | ≥95% |
Target | PROTAC Linkers |
Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |