(R)-(+)-Thiolactomycin

• CAT Number: R025878
• CAS Number: 82079-32-1
• Molecular Formula: C11H14O2S
• Molecular Weight: 210.29
• Purity: ≥95%
• Synonyms: (5R)-4-Hydroxy-3,5-dimethyl-5-[(1E)-2-methyl-1,3-butadien-1-yl]-2(5H)-thiophenone; [R-(E)]-4-Hydroxy-3,5-dimethyl-5-(2-methyl-1,3-butadienyl)-2(5H)-thiophenone; (+)-Thiolactomycin; Antibiotic 2-200; Thiolactomycin?
• Target: Bacterial
• Storage: Store at -20C
• IUPAC Name: (5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1,3-dienyl]thiophen-2-one
• InChI: InChI=1S/C11H14O2S/c1-5-7(2)6-11(4)9(12)8(3)10(13)14-11/h5-6,12H,1H2,2-4H3/b7-6+/t11-/m1/s1
• InChIKey: SYQNUQSGEWNWKV-XUIVZRPNSA-N
• SMILES: CC1=C(C(SC1=O)(C)C=C(C)C=C)O

(R)-(+)-Thiolactomycin（Cat No.:R025878）is a naturally occurring antibiotic known for its inhibitory action against bacterial fatty acid synthesis. It specifically targets and inhibits the enzyme FabB/FabF, essential in the elongation steps of fatty acid biosynthesis, making it a promising candidate for developing new antibacterial agents. Its unique mode of action has garnered interest in research focused on combating antibiotic-resistant bacterial strains. High-purity (R)-(+)-Thiolactomycin is crucial for reliable experimental results, facilitating advancements in antibiotic research and the development of novel therapies for bacterial infections.