(R)-(+)-Verapamil-d6 Hydrochloride

• CAT Number: R049288
• CAS Number: 1795786-09-2
• Molecular Formula: C₂₇H₃₃D₆ClN₂O₄
• Molecular Weight: 497.10
• Purity: ≥95%
• Synonyms: (αR)-α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)benzeneacetonitrile-d6 Hydrochloride; (R)-Verapamil-d6 Hydrochloride; Dexverapamil-d6 Hydrochloride; LU 33925-d6; NSC 632821-d6
• Storage: Store at +4C
• IUPAC Name: (2R)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)pentanenitrile;hydrochloride
• InChI: InChI=1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,20H,8,13-16H2,1-7H3;1H/t27-;/m1./s1/i1D3,2D3
• InChIKey: DOQPXTMNIUCOSY-JBRXLGGISA-N
• SMILES: CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl

(R)-(+)-Verapamil-d6 Hydrochloride（Cat No.:R049288） is a deuterated variant of the R-enantiomer of verapamil, incorporating six deuterium atoms to enhance its analytical detection and stability. This form is crucial for studying the enantiospecific pharmacodynamics and pharmacokinetics of verapamil, a calcium channel blocker used primarily in treating hypertension and cardiac conditions. The hydrochloride salt form improves solubility, facilitating its application in various experimental setups. Widely used in NMR spectroscopy and mass spectrometry, this compound allows researchers to achieve precise, reliable results in the development and optimization of cardiovascular therapies.