For research use only. Not for therapeutic Use.
(R)-VT104 is the R-enantiomer of VT104. (R)-VT104 shows an IC50 value of 0.1-1 μΜ for firefly luciferase. VT104 is an orally active and pan-TEAD auto-palmitoylation inhibitor[1].
| Catalog Number | I041800 |
| CAS Number | 2417718-26-2 |
| Synonyms | N-[(1R)-1-pyridin-2-ylethyl]-5-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxamide |
| Molecular Formula | C25H19F3N2O |
| Purity | ≥95% |
| InChI | InChI=1S/C25H19F3N2O/c1-16(23-7-2-3-14-29-23)30-24(31)19-10-13-22-18(15-19)5-4-6-21(22)17-8-11-20(12-9-17)25(26,27)28/h2-16H,1H3,(H,30,31)/t16-/m1/s1 |
| InChIKey | AAZUPSFRSHFTGV-MRXNPFEDSA-N |
| SMILES | CC(C1=CC=CC=N1)NC(=O)C2=CC3=C(C=C2)C(=CC=C3)C4=CC=C(C=C4)C(F)(F)F |
| Reference | [1]. Konradi, Andrei W, et al. Preparation of substituted naphthalene-2-carboxamide derivatives useful for treatment of cancer. WO2020097389. |
