For research use only. Not for therapeutic Use.
(R)-VX-11e (Compound 1) is an ERK2 inhibitor[1].
| Catalog Number | I040626 |
| CAS Number | 1680187-43-2 |
| Synonyms | 4-[2-(2-chloro-4-fluoroanilino)-5-methylpyrimidin-4-yl]-N-[(1R)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide |
| Molecular Formula | C24H20Cl2FN5O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C24H20Cl2FN5O2/c1-13-10-29-24(31-19-6-5-17(27)9-18(19)26)32-22(13)15-8-20(28-11-15)23(34)30-21(12-33)14-3-2-4-16(25)7-14/h2-11,21,28,33H,12H2,1H3,(H,30,34)(H,29,31,32)/t21-/m0/s1 |
| InChIKey | WUTVMXLIGHTZJC-NRFANRHFSA-N |
| SMILES | CC1=CN=C(N=C1C2=CNC(=C2)C(=O)NC(CO)C3=CC(=CC=C3)Cl)NC4=C(C=C(C=C4)F)Cl |
| Reference | [1]. Vanderpool D, et al. Residence time and kinetic efficiency analysis of extracellular signal-regulated kinase 2 inhibitors. Anal Biochem. 2015 Mar 15;473:46-52. |
