For research use only. Not for therapeutic Use.
R110 is a potent, competitive inhibitor of macrophage migration inhibitory factor 2 (MIF2) tautomerase with an IC50 of 15 μM. R110 has the potential for the research of cancer diseases[1].
| Catalog Number | I044176 |
| CAS Number | 1985622-33-0 |
| Synonyms | 2-amino-N-butyl-5-(4-chlorophenyl)thiophene-3-carboxamide |
| Molecular Formula | C15H17ClN2OS |
| Purity | ≥95% |
| InChI | InChI=1S/C15H17ClN2OS/c1-2-3-8-18-15(19)12-9-13(20-14(12)17)10-4-6-11(16)7-5-10/h4-7,9H,2-3,8,17H2,1H3,(H,18,19) |
| InChIKey | IADRJQICSPVBQR-UHFFFAOYSA-N |
| SMILES | CCCCNC(=O)C1=C(SC(=C1)C2=CC=C(C=C2)Cl)N |
| Reference | [1]. Xiao Z, et al. Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione Derivative Inhibits d-Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells. J Med Chem. 2022 Feb 10;65(3):2059-2077. |
