For research use only. Not for therapeutic Use.
R803 is an effective HCV replication inhibitor. R803 is substantially more potent against genotype 1a and 1b replicons (EC50, ~30 nM) than against the genotype 2a replicon (EC50, ~1,000 nM).
| Catalog Number | I013317 |
| CAS Number | 67700-30-5 |
| Molecular Formula | C₁₇H₁₄O₃ |
| Purity | ≥95% |
| Target | HCV |
| Solubility | DMSO |
| IUPAC Name | 2-(3-phenyl-1-benzofuran-7-yl)propanoic acid |
| InChI | InChI=1S/C17H14O3/c1-11(17(18)19)13-8-5-9-14-15(10-20-16(13)14)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19) |
| InChIKey | ODZUWQAFWMLWCF-UHFFFAOYSA-N |
| SMILES | CC(C1=CC=CC2=C1OC=C2C3=CC=CC=C3)C(=O)O |
| Reference | [1]. Huang P, et al. Discovery and characterization of substituted diphenyl heterocyclic compounds as potent and selective inhibitors of hepatitis C virus replication. Antimicrob Agents Chemother. 2008 Apr;52(4):1419-29. |
