For research use only. Not for therapeutic Use.
Rabeprazole-d4 sodium, a premium pharmaceutical research compound designed for advanced gastrointestinal and proton pump inhibitor studies. As a deuterated analog of Rabeprazole sodium, it offers enhanced stability and improved pharmacokinetic properties. Rabeprazole-d4 sodium is ideal for use in pharmacological and biochemical research, providing precise and reliable data for your studies. This high-purity compound ensures consistent results, aiding in the development of novel therapies for acid-related disorders such as GERD and peptic ulcers. Trusted by leading laboratories, Rabeprazole-d4 sodium is your go-to solution for cutting-edge gastrointestinal research. Unlock new possibilities in acid-related disorder treatment with Rabeprazole-d4 sodium, where innovation meets reliability.
| Catalog Number | S000197 |
| Molecular Formula | C18H16D4N3NaO3S |
| Purity | ≥95% |
| IUPAC Name | sodium;4,5,6,7-tetradeuterio-2-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl]benzimidazol-1-ide |
| InChI | InChI=1S/C18H20N3O3S.Na/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18;/h3-4,6-9H,5,10-12H2,1-2H3;/q-1;+1/i3D,4D,6D,7D; |
| InChIKey | KRCQSTCYZUOBHN-SWSVCJOSSA-N |
| SMILES | [2H]C1=C(C(=C2C(=C1[2H])[N-]C(=N2)S(=O)CC3=NC=CC(=C3C)OCCCOC)[2H])[2H].[Na+] |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Tara A Shea, et al. Identification of Proton-Pump Inhibitor Drugs That Inhibit Trichomonas Vaginalis Uridine Nucleoside Ribohydrolase. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1080-4. [3]. Mengli Gu, et al. Rabeprazole Exhibits Antiproliferative Effects on Human Gastric Cancer Cell Lines. Oncol Lett. 2014 Oct;8(4):1739-1744. [4]. Aly A M Shaalan, et al. Supplement With Calcium or Alendronate Suppresses Osteopenia Due to Long Term Rabeprazole Treatment in Female Mice: Influence on Bone TRAP and Osteopontin Levels. Front Pharmacol. 2020 May 13;11:583. |
