Rabeprazole

For research use only. Not for therapeutic Use.

  • CAT Number: I000637
  • CAS Number: 117976-89-3
  • Molecular Formula: C18H21N3O3S
  • Molecular Weight: 359.44
  • Purity: ≥95%
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Rabeprazole (Cat No.:I000637) belongs to the class of second-generation proton pump inhibitors (PPIs), which are known for irreversibly blocking the activity of gastric H+/K+-ATPase. In addition to its PPI activity, Rabeprazole has been found to induce apoptosis. It also acts as an inhibitor of uridine nucleoside ribohydrolase (UNH) with an IC50 of 0.3 μM. Researchers can use Rabeprazole to study gastric ulcerations and gastroesophageal reflux.


Catalog Number I000637
CAS Number 117976-89-3
Synonyms

2-(((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole

Molecular Formula C18H21N3O3S
Purity ≥95%
Target Proton Pump
Solubility 10 mM in DMSO
Storage -20°C
IUPAC Name 2-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl]-1H-benzimidazole
InChI InChI=1S/C18H21N3O3S/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18/h3-4,6-9H,5,10-12H2,1-2H3,(H,20,21)
InChIKey YREYEVIYCVEVJK-UHFFFAOYSA-N
SMILES CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCCCOC
Reference

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<br>[1]. http://www.drugbank.ca/drugs/DB01129
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