rac 8-Hydroxy Efavirenz-d4

• CAT Number: C000858
• CAS Number: 1246812-30-5
• Molecular Formula: C₁₄H₅D₄ClF₃NO₃
• Molecular Weight: 335.7
• Purity: ≥95%
• Synonyms: 6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; 8-Hydroxyefavirenz
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Appearance: White to Off-White Solid
• Storage: -20°C
• IUPAC Name: 6-chloro-8-hydroxy-4-[2-(2,2,3,3-tetradeuteriocyclopropyl)ethynyl]-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
• InChI: InChI=1S/C14H9ClF3NO3/c15-8-5-9-11(10(20)6-8)19-12(21)22-13(9,14(16,17)18)4-3-7-1-2-7/h5-7,20H,1-2H2,(H,19,21)/i1D2,2D2
• InChIKey: OOVOMPCQLMFEDT-LNLMKGTHSA-N
• SMILES: C1CC1C#CC2(C3=C(C(=CC(=C3)Cl)O)NC(=O)O2)C(F)(F)F

Rac 8-Hydroxy Efavirenz-d4 (Cat No.:C000858) is a racemic mixture of deuterium-labeled 8-hydroxy efavirenz, a derivative of the antiretroviral drug efavirenz. The “d4” notation indicates that four hydrogen atoms in the molecule are replaced with deuterium, a stable isotope of hydrogen. This labeling allows researchers to study the metabolism, pharmacokinetics, and interactions of efavirenz in biological systems accurately. Rac 8-Hydroxy Efavirenz-d4 is a valuable tool in pharmaceutical research, aiding in the understanding of drug effects, improving drug design, and advancing the treatment of HIV infections.

Reference

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