(Rac)-Bedaquiline-d6

• CAT Number: S000469
• CAS Number: 654655-80-8
• Molecular Formula: C32H25D6BrN2O2
• Molecular Weight: 561.54
• Purity: ≥95%
• IUPAC Name: 4-[bis(trideuteriomethyl)amino]-1-(6-bromo-2-methoxyquinolin-3-yl)-2-naphthalen-1-yl-1-phenylbutan-2-ol
• InChI: InChI=1S/C32H31BrN2O2/c1-35(2)19-18-32(36,28-15-9-13-22-10-7-8-14-26(22)28)30(23-11-5-4-6-12-23)27-21-24-20-25(33)16-17-29(24)34-31(27)37-3/h4-17,20-21,30,36H,18-19H2,1-3H3/i1D3,2D3
• InChIKey: QUIJNHUBAXPXFS-WFGJKAKNSA-N
• SMILES: CN(C)CCC(C1=CC=CC2=CC=CC=C21)(C(C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O

(Rac)-Bedaquiline-d6（Cat No.:S000469） is a deuterated form of bedaquiline, with six hydrogen atoms replaced by deuterium. This version is utilized in pharmaceutical research to understand the drug’s pharmacokinetic properties and metabolic stability. Bedaquiline is a novel antituberculosis agent, specifically targeting Mycobacterium tuberculosis, the bacteria responsible for tuberculosis. It operates by inhibiting the ATP synthase in bacterial cells, effectively starving them of energy. The racemic (rac) form indicates a mixture of both enantiomers of the molecule.