For research use only. Not for therapeutic Use.
(Rac)-Cemsidomide(Cat No.:I043445)is a small molecule inhibitor that targets cereblon, a protein involved in regulating protein homeostasis through the ubiquitin-proteasome system. By binding to cereblon, (Rac)-Cemsidomide modulates the degradation of specific proteins that play a role in tumor cell survival and proliferation. This compound is being investigated for its potential therapeutic applications in cancer treatment, particularly in hematological malignancies such as multiple myeloma. (Rac)-Cemsidomide’s ability to induce selective protein degradation offers a promising approach for targeting cancer cells and overcoming resistance to existing therapies.
CAS Number | 2504233-68-3 |
Synonyms | 3-[6-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-2-oxobenzo[cd]indol-1-yl]piperidine-2,6-dione |
Molecular Formula | C28H27N3O4 |
Purity | ≥95% |
IUPAC Name | 3-[6-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-2-oxobenzo[cd]indol-1-yl]piperidine-2,6-dione |
InChI | InChI=1S/C28H27N3O4/c32-25-11-10-24(27(33)29-25)31-23-9-8-20(21-2-1-3-22(26(21)23)28(31)34)16-18-4-6-19(7-5-18)17-30-12-14-35-15-13-30/h1-9,24H,10-17H2,(H,29,32,33) |
InChIKey | MUKCJOOKCZSQNW-UHFFFAOYSA-N |
SMILES | C1CC(=O)NC(=O)C1N2C3=C4C(=C(C=C3)CC5=CC=C(C=C5)CN6CCOCC6)C=CC=C4C2=O |
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