For research use only. Not for therapeutic Use.
(Rac)-EC5026 ((Rac)-BPN-19186) is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) extracted from patent WO2019156991A1, page 39, has a Ki of 0.06 nM. (Rac)-EC5026 can be used for the research of Parkinson’s disease and dementia with Lewy Bodies (DLB)[1].
(Rac)-EC5026 inhibits soluble epoxide hydrolase (sEH), with a Ki of 0.06 nM[1].
| Catalog Number | I044516 |
| CAS Number | 1809885-55-9 |
| Synonyms | 1-[3-fluoro-4-(trifluoromethoxy)phenyl]-3-[1-(2-methylbutanoyl)piperidin-4-yl]urea |
| Molecular Formula | C18H23F4N3O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H23F4N3O3/c1-3-11(2)16(26)25-8-6-12(7-9-25)23-17(27)24-13-4-5-15(14(19)10-13)28-18(20,21)22/h4-5,10-12H,3,6-9H2,1-2H3,(H2,23,24,27) |
| InChIKey | LHRXHTKENPCGSZ-UHFFFAOYSA-N |
| SMILES | CCC(C)C(=O)N1CCC(CC1)NC(=O)NC2=CC(=C(C=C2)OC(F)(F)F)F |
| Reference | [1]. Hammock BD, et, al. Methods of inhibiting formation of alpha synuclein aggregates. WO2019156991A1. |
