rac Guaifenesin-d5

• CAT Number: R049132
• CAS Number: 1329563-41-8
• Molecular Formula: C10H14O4
• Molecular Weight: 203.249
• Purity: ≥95%
• Synonyms: 3-(o-Methoxyphenoxy)-1,2-propanediol-d5; Guaiacol Glyceryl-d5 Ether; Robitussin-d5
• Storage: Store at -20°C
• IUPAC Name: 1,1,2,3,3-pentadeuterio-3-(2-methoxyphenoxy)propane-1,2-diol
• InChI: InChI=1S/C10H14O4/c1-13-9-4-2-3-5-10(9)14-7-8(12)6-11/h2-5,8,11-12H,6-7H2,1H3/i6D2,7D2,8D
• InChIKey: HSRJKNPTNIJEKV-RORPNYJOSA-N
• SMILES: [2H]C([2H])(C([2H])(C([2H])([2H])OC1=CC=CC=C1OC)O)O

rac Guaifenesin-d5 is a deuterated form of the racemic mixture of guaifenesin, where five hydrogen atoms have been replaced with deuterium. This isotopically labeled compound is commonly used in pharmaceutical and clinical research, particularly in studies related to the metabolism, pharmacokinetics, and pharmacodynamics of guaifenesin, a widely used expectorant. The deuterium labeling allows for precise tracking and enhanced accuracy in analytical techniques such as mass spectrometry, providing reliable data on the absorption, distribution, metabolism, and excretion of the drug. rac Guaifenesin-d5 is an essential tool for researchers aiming to better understand the drug’s action, optimize dosing regimens, and develop improved formulations for the treatment of respiratory conditions.