For research use only. Not for therapeutic Use.
Rac-irofulven is a synthetic anticancer agent derived from the natural product illudin S, found in the Jack O’Lantern mushroom (Omphalotus illudens). It is a racemic mixture, containing equal parts of both enantiomers. Rac-irofulven has shown potent antitumor activity by inducing DNA damage in cancer cells. Research focuses on its mechanisms of action, efficacy across different cancer types, and potential development as a chemotherapeutic agent offering advantages over conventional treatments.
| Catalog Number | R049831 |
| CAS Number | 187277-46-9 |
| Synonyms | 6’-Hydroxy-3’-(hydroxymethyl)-2’,4’,6’-trimethylspiro[cyclopropane-1,5’-[5H]inden]-7’(6’H)-one; (+/-)-Hydroxymethylacylfulvene; |
| Molecular Formula | C15H18O3 |
| Purity | ≥95% |
| Storage | Store at RT |
| IUPAC Name | 5'-hydroxy-1'-(hydroxymethyl)-2',5',7'-trimethylspiro[cyclopropane-1,6'-indene]-4'-one |
| InChI | InChI=1S/C15H18O3/c1-8-6-10-12(11(8)7-16)9(2)15(4-5-15)14(3,18)13(10)17/h6,16,18H,4-5,7H2,1-3H3 |
| InChIKey | NICJCIQSJJKZAH-UHFFFAOYSA-N |
| SMILES | CC1=C(C2=C(C3(CC3)C(C(=O)C2=C1)(C)O)C)CO |
