(Rac)-JBJ-04-125-02

• CAT Number: I047437
• CAS Number: 2140807-05-0
• Molecular Formula: C29H26FN5O3S
• Molecular Weight: 543.61
• Purity: ≥95%
• Storage: 3 years -20°C powder
• SMILES: OC1=CC=C(F)C=C1C(N2CC3=C(C=C(C=C3)C4=CC=C(C=C4)N5CCNCC5)C2=O)C(=O)NC6=NC=CS6

(Rac)-JBJ-04-125-02 (JBJ-04-125-02 racemate) is a mutant-selective allosteric inhibitor of Epidermal growth factor receptor (EGFR) with potential anticancer activity.

Reference

[1] Ciric To, et al. Cancer Discov. 2019 Jul;9(7):926-943.