(Rac)-LM11A-31 dihydrochloride

• CAT Number: I017488
• CAS Number: 1214672-15-7
• Molecular Formula: C₁₂H₂₇Cl₂N₃O₂
• Molecular Weight: 316.27
• Purity: ≥95%

(Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride, a non-peptide p75NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist[1].

Reference

[1]. Elshaer SL, et al. Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinalvascular permeability in mice via inhibition of inflammation and the RhoA kinase pathway. Diabetologia. 2019 Aug;62(8):1488-1500.