rac Perhexiline Maleate

• CAT Number: R046297
• CAS Number: 6724-53-4
• Molecular Formula: C19H35N • C4H4O4
• Molecular Weight: 393.60
• Purity: ≥95%
• Synonyms: 2-(2,2-Dicyclohexylethyl)piperidine Maleate; (+/-)-2-(2,2-Dicyclohexylethyl)piperidine Maleate
• Target: CPT1
• Solubility: Soluble in DMSO
• Storage: Store at -20°C
• IUPAC Name: (Z)-but-2-enedioic acid;2-(2,2-dicyclohexylethyl)piperidine
• InChI: InChI=1S/C19H35N.C4H4O4/c1-3-9-16(10-4-1)19(17-11-5-2-6-12-17)15-18-13-7-8-14-20-18;5-3(6)1-2-4(7)8/h16-20H,1-15H2;1-2H,(H,5,6)(H,7,8)/b;2-1-
• InChIKey: JDZOTSLZMQDFLG-BTJKTKAUSA-N
• SMILES: C1CCC(CC1)C(CC2CCCCN2)C3CCCCC3.C(=C\C(=O)O)\C(=O)O

rac-Perhexiline Maleate（Cat No.:R046297）is a chiral compound used as a metabolic modulator, primarily in treating angina and heart failure. It works by inhibiting mitochondrial carnitine palmitoyltransferase-1 (CPT-1), shifting myocardial energy metabolism from fatty acid oxidation to glucose utilization, which is more oxygen-efficient. This metabolic shift helps improve cardiac efficiency and reduce oxygen demand in ischemic heart conditions. rac-Perhexiline Maleate’s role in heart failure management also makes it a candidate for studying metabolic therapies in cardiology. Due to variability in metabolism, therapeutic monitoring is essential to avoid toxicity.

Reference

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