(Rac)-RP-6306

• CAT Number: I043978
• CAS Number: 2719749-28-5
• Molecular Formula: C18H20N4O2
• Molecular Weight: 324.38
• Purity: ≥95%
• Synonyms: 2-amino-1-(3-hydroxy-2,6-dimethylphenyl)-5,6-dimethylpyrrolo[2,3-b]pyridine-3-carboxamide
• InChI: InChI=1S/C18H20N4O2/c1-8-5-6-13(23)10(3)15(8)22-16(19)14(17(20)24)12-7-9(2)11(4)21-18(12)22/h5-7,23H,19H2,1-4H3,(H2,20,24)
• InChIKey: ARBRHWRTXPWZGN-UHFFFAOYSA-N
• SMILES: CC1=C(C(=C(C=C1)O)C)N2C(=C(C3=C2N=C(C(=C3)C)C)C(=O)N)N

(Rac)-RP-6306 (compound 181) is a potent Myt1 inhibitor with an IC50 of <10 nM. (Rac)-RP-6306 (compound 181) has anticancer effects[1].

Reference

[1]. Daniel Durocher, et al. Methods of using myt1 inhibitors. WO2021195782A1.