(Rac)-Ruxolitinib-d8

For research use only. Not for therapeutic Use.

  • CAT Number: S000192
  • CAS Number: 1794791-38-0
  • Molecular Formula: C17H10D8N6
  • Molecular Weight: 314.41
  • Purity: ≥95%
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(Rac)-Ruxolitinib-d8 (CAS: 1794791-38-0), a premium pharmaceutical research compound designed for advanced oncology and immunology studies. As a deuterated analog of Ruxolitinib, it offers enhanced stability and improved pharmacokinetic properties. (Rac)-Ruxolitinib-d8 is ideal for use in pharmacological and biochemical research, providing precise and reliable data for your studies. This high-purity compound ensures consistent results, aiding in the development of novel therapies for myeloproliferative disorders and other immune-related conditions. Trusted by leading laboratories, (Rac)-Ruxolitinib-d8 is your go-to solution for cutting-edge cancer and immunology research. Unlock new possibilities in treatment with (Rac)-Ruxolitinib-d8, where innovation meets reliability.


Catalog Number S000192
CAS Number 1794791-38-0
Molecular Formula C17H10D8N6
Purity ≥95%
IUPAC Name 3-(2,2,3,3,4,4,5,5-octadeuteriocyclopentyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile
InChI InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/i1D2,2D2,3D2,4D2
InChIKey HFNKQEVNSGCOJV-SVYQBANQSA-N
SMILES [2H]C1(C(C(C(C1([2H])[2H])([2H])[2H])([2H])[2H])C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3)[2H]
Reference

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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