For research use only. Not for therapeutic Use.
rac Tenofovir-d6(Cat No.:R003466) is a deuterated version of racemic Tenofovir, where six hydrogen atoms are replaced with deuterium. This isotopic modification enhances the compound’s chemical stability, making it highly useful for detailed pharmacokinetic and metabolic studies of Tenofovir, an antiretroviral medication used primarily to treat HIV and hepatitis B infections. The deuterated form facilitates the precise tracing of the drug’s absorption, distribution, metabolism, and excretion processes, improving the understanding of its pharmacological profile and effectiveness.
Catalog Number | R003466 |
CAS Number | 1020719-94-1 |
Synonyms | 2(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-d6-phosphonic Acid;?9-(2-Phosphonomethoxypropyl)adenine-d6; PMPA-d6; rac-GS-1278-d6; rac-Tenefovir-d6; |
Molecular Formula | C9H14N5O4P |
Purity | ≥95% |
Storage | -20°C |
IUPAC Name | [1-(6-aminopurin-9-yl)-1,1,2,3,3,3-hexadeuteriopropan-2-yl]oxymethylphosphonic acid |
InChI | InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/i1D3,2D2,6D |
InChIKey | SGOIRFVFHAKUTI-CUYPRXAISA-N |
SMILES | [2H]C([2H])([2H])C([2H])(C([2H])([2H])N1C=NC2=C(N=CN=C21)N)OCP(=O)(O)O |