Radafaxine hydrochloride

For research use only. Not for therapeutic Use.

  • CAT Number: I000308
  • CAS Number: 106083-71-0
  • Molecular Formula: C13H19Cl2NO2
  • Molecular Weight: 292.20
  • Purity: ≥95%
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Radafaxine hydrochloride(Cat No.:I000308)is a selective serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) that has been investigated as a potential treatment for disorders like depression, anxiety, and attention deficit hyperactivity disorder (ADHD). It works by increasing the levels of serotonin, norepinephrine, and dopamine in the brain, which are neurotransmitters involved in regulating mood, attention, and cognitive function. Radafaxine hydrochloride is still under clinical development and is being explored for its ability to improve mood, focus, and reduce symptoms of anxiety and depression. Its safety and efficacy in various mental health conditions are still being evaluated.


Catalog Number I000308
CAS Number 106083-71-0
Molecular Formula C13H19Cl2NO2
Purity ≥95%
Solubility DMSO: ≥ 38 mg/mL
Storage Store at -20°C
IUPAC Name (2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol;hydrochloride
InChI InChI=1S/C13H18ClNO2.ClH/c1-9-13(16,17-8-12(2,3)15-9)10-5-4-6-11(14)7-10;/h4-7,9,15-16H,8H2,1-3H3;1H/t9-,13+;/m0./s1
InChIKey ORXTVTDGPVINDN-BTJVGWIPSA-N
SMILES C[C@H]1[C@@](OCC(N1)(C)C)(C2=CC(=CC=C2)Cl)O.Cl
Reference

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<br>[1]. Xu H, et al. Stereoselective analysis of hydroxybupropion and application to drug interaction studies. Chirality. 2007 Mar;19(3):163-70.
<br>[2]. Bondarev ML, et al. Behavioral and biochemical investigations of bupropion metabolites. Eur J Pharmacol. 2003 Aug 1;474(1):85-93.
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