For research use only. Not for therapeutic Use.
Radequinil (AC-3933) is a benzodiazepine receptor (BzR) partial inverse agonist. AC-3933 binds to GABA(-) and GABA(+) ligand with Kis of 5.15 and 6.11 nM, respectively[1].
| Catalog Number | I008965 |
| CAS Number | 219846-31-8 |
| Synonyms | 5-(3-methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-1H-1,6-naphthyridin-2-one |
| Molecular Formula | C18H14N4O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H14N4O3/c1-10-20-17(22-25-10)14-9-13-15(21-18(14)23)6-7-19-16(13)11-4-3-5-12(8-11)24-2/h3-9H,1-2H3,(H,21,23) |
| InChIKey | JQOFKKWHXGQABB-UHFFFAOYSA-N |
| SMILES | CC1=NC(=NO1)C2=CC3=C(C=CN=C3C4=CC(=CC=C4)OC)NC2=O |
| Reference | [1]. Hashimoto T, et al. Pharmacological properties of AC-3933, a novel benzodiazepine receptor partial inverse agonist. Neuroscience. 2014 Jan 3;256:352-9. |
