Ramifenazone

• CAT Number: I003328
• CAS Number: 3615-24-5
• Molecular Formula: C14H19N3O
• Molecular Weight: 245.32
• Purity: ≥95%
• Synonyms: Isopyrin; Isopirina
• Target: Bacterial
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: 1,5-dimethyl-2-phenyl-4-(propan-2-ylamino)pyrazol-3-one
• InChI: InChI=1S/C14H19N3O/c1-10(2)15-13-11(3)16(4)17(14(13)18)12-8-6-5-7-9-12/h5-10,15H,1-4H3
• InChIKey: XOZLRRYPUKAKMU-UHFFFAOYSA-N
• SMILES: CC1=C(C(=O)N(N1C)C2=CC=CC=C2)NC(C)C

Ramifenazone(CAT: I003328), also known as RGH-2202, is a pharmaceutical compound that exhibits a wide range of pharmacological properties. It acts as an anti-inflammatory and analgesic agent, with reported activity in inhibiting prostaglandin synthesis. Ramifenazone has also shown antioxidant effects, potentially contributing to its anti-inflammatory properties. Furthermore, it displays antiplatelet activity by inhibiting platelet aggregation. The compound has been investigated for its potential therapeutic applications in the treatment of various conditions, including rheumatoid arthritis, osteoarthritis, and pain management.

Reference

1.Dowling, Geraldine, and Edward Malone. "Analytical strategy for the confirmatory analysis of the non-steroidal anti-inflammatory drugs firocoxib, propyphenazone, ramifenazone and piroxicam in bovine plasma by liquid chromatography tandem mass spectrometry." Journal of pharmaceutical and biomedical analysis 56.2 (2011): 359-365.
2.Nehra, Bhupender, et al. "Recent advancements in the development of bioactive pyrazoline derivatives." European Journal of Medicinal Chemistry (2020): 112666.
3.Kumar, R. Surendra, et al. "Anti-inflammatory and antimicrobial activities of novel pyrazole analogues." Saudi journal of biological sciences 23.5 (2016): 614-620.