For research use only. Not for therapeutic Use.
Ramiprilat(Cat No.:I010747) is the active metabolite of the drug Ramipril, which is an angiotensin-converting enzyme (ACE) inhibitor used in the treatment of high blood pressure, heart failure, and to reduce the risk of heart attack, and stroke. Ramiprilat works by inhibiting the action of ACE, an enzyme that is responsible for converting angiotensin I to angiotensin II. Angiotensin II is a potent vasoconstrictor that can raise blood pressure and cause other cardiovascular effects. By inhibiting ACE and reducing the production of angiotensin II, Ramiprilat can help to lower blood pressure, improve heart function, and reduce the risk of cardiovascular events.
Catalog Number | I010747 |
CAS Number | 87269-97-4 |
Synonyms | (2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]-1-oxopropyl]octahydro-cyclopenta[b]pyrrole-2-carboxylic acid |
Molecular Formula | C21H28N2O5 |
Purity | ≥95% |
Target | ACE |
Solubility | Soluble in DMSO |
Storage | Store at -20°C |
IUPAC Name | (2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid |
InChI | InChI=1S/C21H28N2O5/c1-13(22-16(20(25)26)11-10-14-6-3-2-4-7-14)19(24)23-17-9-5-8-15(17)12-18(23)21(27)28/h2-4,6-7,13,15-18,22H,5,8-12H2,1H3,(H,25,26)(H,27,28)/t13-,15-,16-,17-,18-/m0/s1 |
InChIKey | KEDYTOTWMPBSLG-HILJTLORSA-N |
SMILES | CC(C(=O)N1C2CCCC2CC1C(=O)O)NC(CCC3=CC=CC=C3)C(=O)O |