Ramosetron-d3 Hydrochloride

• CAT Number: R048206
• CAS Number: 1330266-04-0
• Molecular Formula: C17H18ClN3O
• Molecular Weight: 318.819
• Purity: ≥95%
• Synonyms: [1-(Methyl-d3)-1H-indol-3-yl][(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]methanone Hydrochloride; (-)-(R)-5-[(1-(Methyl-d3)-1H-indol-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H- benzimidazole Monohydrochloride; (R)-(-)-Ramosetron-d3 Hydrochloride; Irribow
• Storage: Store at -20°C
• IUPAC Name: [(5R)-4,5,6,7-tetrahydro-3H-benzimidazol-5-yl]-[1-(trideuteriomethyl)indol-3-yl]methanone;hydrochloride
• InChI: InChI=1S/C17H17N3O.ClH/c1-20-9-13(12-4-2-3-5-16(12)20)17(21)11-6-7-14-15(8-11)19-10-18-14;/h2-5,9-11H,6-8H2,1H3,(H,18,19);1H/t11-;/m1./s1/i1D3
• InChIKey: XIXYTCLDXQRHJO-LUVKJXGXSA-N
• SMILES: [2H]C([2H])([2H])N1C=C(C2=CC=CC=C21)C(=O)[C@@H]3CCC4=C(C3)NC=N4.Cl

Ramosetron-d3 Hydrochloride is a deuterated form of ramosetron hydrochloride, where three hydrogen atoms are replaced with deuterium. Ramosetron is a selective 5-HT3 serotonin receptor antagonist used to manage nausea and vomiting, particularly in chemotherapy-induced settings. The deuterium labeling in ramosetron-d3 Hydrochloride serves as an internal standard in mass spectrometry and NMR spectroscopy, enhancing the accuracy of quantification and structural analysis. In pharmaceutical research, it aids in studies of drug metabolism, pharmacokinetics, and interactions. The stable isotope labeling ensures precise and reliable data in analytical applications, contributing to drug development and efficacy evaluations.