For research use only. Not for therapeutic Use.
Ranitidine S-oxide is the metabolite of Ranitidine (HY-B0693). Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion[1][2].
| Catalog Number | R006380 |
| CAS Number | 73851-70-4 |
| Synonyms | (E)-1-N’-[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfinyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine |
| Molecular Formula | C13H22N4O4S |
| Purity | ≥95% |
| InChI | InChI=1S/C13H22N4O4S/c1-14-13(9-17(18)19)15-6-7-22(20)10-12-5-4-11(21-12)8-16(2)3/h4-5,9,14-15H,6-8,10H2,1-3H3/b13-9+ |
| InChIKey | SKHXRNHSZTXSLP-UKTHLTGXSA-N |
| SMILES | CNC(=C[N+](=O)[O-])NCCS(=O)CC1=CC=C(O1)CN(C)C |
| Reference | [1]. Cross DM, et al. Kinetics of ranitidine metabolism in dog and rat isolated hepatocytes. Xenobiotica. 1995 Apr;25(4):367-75. [2]. Leucuta A, et al. A pharmacokinetic interaction study between omeprazole and the H2-receptor antagonist ranitidine. Drug Metabol Drug Interact. 2004;20(4):273-81. |
