For research use only. Not for therapeutic Use.
RB-OPD (NO-red) is a o-phenylenediamine (OPD)-locked rhodamine nitric oxide (NO) fluorescent probe with great sensitivity and selectivity (λex=550 nm, λem=590 nm)[1].
RB-OPD (compound 1) exhibits “turn-on” type fluorogenic and chromogenic behavior toward NO in aqueous solution with great sensitivity and selectivity, and it can be used for the sensing of NO under normal physiological conditions. NO-red is composed of two moieties: rhodamine B spirolactam as the potential strong fluorophore and chromophore, and o-phenylenediamine as an NO-reactive group in a lactam form as a “masked” NO-sensitive modulator[1].
| Catalog Number | I044996 |
| CAS Number | 1034863-51-8 |
| Synonyms | 2-(2-aminophenyl)-3′,6′-bis(diethylamino)spiro[isoindole-3,9′-xanthene]-1-one |
| Molecular Formula | C34H36N4O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C34H36N4O2/c1-5-36(6-2)23-17-19-27-31(21-23)40-32-22-24(37(7-3)8-4)18-20-28(32)34(27)26-14-10-9-13-25(26)33(39)38(34)30-16-12-11-15-29(30)35/h9-22H,5-8,35H2,1-4H3 |
| InChIKey | FLFCPVCPMCLBEW-UHFFFAOYSA-N |
| SMILES | CCN(CC)C1=CC2=C(C=C1)C3(C4=C(O2)C=C(C=C4)N(CC)CC)C5=CC=CC=C5C(=O)N3C6=CC=CC=C6N |
| Reference | [1]. Hong Zheng, et al. Fluorogenic and chromogenic rhodamine spirolactam based probe for nitric oxide by spiro ring opening reaction. Org Lett. 2008 Jun 19;10(12):2357-60. |
