Rbin-1

• CAT Number: I003164
• CAS Number: 328023-11-6
• Molecular Formula: C13H12N4S
• Molecular Weight: 256.33
• Purity: ≥95%
• Target: Phosphatase
• Solubility: DMSO: ≥ 31 mg/mL
• Storage: 3 years -20C powder

Rbin-1 (CAT: I003164) is a notable compound recognized for its potent and specific inhibitory action on eukaryotic ribosome biogenesis. By targeting this essential cellular process, Rbin-1 interferes with the assembly of ribosomes, which are vital molecular complexes involved in protein synthesis. Its reversible inhibition of ribosome biogenesis may offer valuable insights into the regulation of cellular growth and proliferation, and could potentially lead to the development of therapeutic strategies aimed at conditions where aberrant ribosome biogenesis contributes to disease, such as cancer and certain genetic disorders.

Reference

[1]. Kawashima SA, et al. Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis. Cell. 2016 Oct 6;167(2):512-524.e14.