Reboxetine-d5 Mesylate

• CAT Number: R005419
• CAS Number: 1285918-53-7
• Molecular Formula: C20H27NO6S
• Molecular Weight: 414.528
• Purity: ≥95%
• Synonyms: (2R)-rel-2-[(R)-(2-Ethoxy-d5-phenoxy)phenylmethyl]morpholine Methanesulfonate;?(+/-)-Reboxetine-d5 Mesylate; Davedax-d5; Edronax-d5; FCE 20124-d5; PNU 155905E-d5; PNU 155950E-d5; Reboxetine-d5 Mesilate
• Storage: -20°C
• IUPAC Name: methanesulfonic acid;(2R)-2-[(R)-[2-(1,1,2,2,2-pentadeuterioethoxy)phenoxy]-phenylmethyl]morpholine
• InChI: InChI=1S/C19H23NO3.CH4O3S/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18;1-5(2,3)4/h3-11,18-20H,2,12-14H2,1H3;1H3,(H,2,3,4)/t18-,19-;/m1./s1/i1D3,2D2
• InChIKey: CGTZMJIMMUNLQD-HODPIWSTSA-N
• SMILES: [2H]C([2H])([2H])C([2H])([2H])OC1=CC=CC=C1O[C@@H]([C@H]2CNCCO2)C3=CC=CC=C3.CS(=O)(=O)O

Reboxetine-d5 Mesylate is a deuterium-labeled form of reboxetine, an antidepressant used primarily to treat major depressive disorder. The deuterium labeling enables precise tracking and quantification of reboxetine in pharmacokinetic studies using mass spectrometry. This compound aids in understanding the drug’s metabolism, distribution, and elimination, allowing for more accurate evaluations of its therapeutic efficacy and safety. The mesylate salt form enhances the solubility and stability of reboxetine, facilitating its use in research and clinical settings to optimize dosing regimens and improve antidepressant therapy outcomes.