For research use only. Not for therapeutic Use.
(rel)-Eglumegad(CAT: R042483) is a small molecule compound used in Inflammation & Immunology Research. It acts as an inhibitor of the pro-inflammatory mediator phosphodiesterase 4 (PDE4), which plays a key role in the regulation of cyclic AMP levels within immune cells. By inhibiting PDE4, (rel)-Eglumegad increases cyclic AMP levels, leading to the suppression of inflammatory cytokine production and a reduction in immune cell activation. This mechanism is particularly beneficial in managing inflammatory diseases, including asthma, chronic obstructive pulmonary disease (COPD), and psoriasis. The compound has shown promise in modulating the immune response and alleviating symptoms of chronic inflammatory conditions.
| CAS Number | 176027-90-0 |
| Synonyms | (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid |
| Molecular Formula | C8H11NO4 |
| Purity | ≥95% |
| IUPAC Name | (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid |
| InChI | InChI=1S/C8H11NO4/c9-8(7(12)13)2-1-3-4(5(3)8)6(10)11/h3-5H,1-2,9H2,(H,10,11)(H,12,13)/t3-,4-,5-,8-/m0/s1 |
| InChIKey | VTAARTQTOOYTES-RGDLXGNYSA-N |
| SMILES | C1C[C@]([C@H]2[C@@H]1[C@@H]2C(=O)O)(C(=O)O)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
