Relacatib

• CAT Number: I008995
• CAS Number: 362505-84-8
• Molecular Formula: C27H32N4O6S
• Molecular Weight: 540.64
• Purity: ≥95%
• Synonyms: SB462795; SB-462795; SB 462795; GSK462795; GSK-462795; GSK 462795; D06634;N-((S)-4-methyl-1-(((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-yl)amino)-1-oxopentan-2-yl)benzofuran-2-carboxamide.
• Target: Cathepsin
• Solubility: Soluble in DMSO
• Storage: 0 - 4 °C for short term, or -20 °C for long term
• IUPAC Name: N-[(2S)-4-methyl-1-[[(4S,7R)-7-methyl-3-oxo-1-pyridin-2-ylsulfonylazepan-4-yl]amino]-1-oxopentan-2-yl]-1-benzofuran-2-carboxamide
• InChI: InChI=1S/C27H32N4O6S/c1-17(2)14-21(30-27(34)24-15-19-8-4-5-9-23(19)37-24)26(33)29-20-12-11-18(3)31(16-22(20)32)38(35,36)25-10-6-7-13-28-25/h4-10,13,15,17-18,20-21H,11-12,14,16H2,1-3H3,(H,29,33)(H,30,34)/t18-,20+,21+/m1/s1
• InChIKey: BWYBBMQLUKXECQ-GIVPXCGWSA-N
• SMILES: CC1CCC(C(=O)CN1S(=O)(=O)C2=CC=CC=N2)NC(=O)C(CC(C)C)NC(=O)C3=CC4=CC=CC=C4O3

Relacatib(CAT: I008995) is a potent and selective inhibitor of cathepsin K, a cysteine protease crucial in bone resorption and collagen degradation. This compound is widely utilized in research focused on osteoporosis, osteoarthritis, and other bone-related disorders. By inhibiting cathepsin K, Relacatib effectively reduces excessive bone turnover, making it a valuable tool in studying bone metabolism and potential therapeutic strategies. Its high purity and stability ensure reliable experimental results, supporting drug discovery and development. Ideal for researchers exploring protease activity and bone health, Relacatib contributes to advancements in metabolic and skeletal disease research.