Remdesivir

• CAT Number: I009001
• CAS Number: 1809249-37-3
• Molecular Formula: C27H35N6O8P
• Molecular Weight: 602.58
• Purity: 98%
• Synonyms: Remdesivir; GS-5734; GS 5734; GS5734.;2-ethylbutyl ((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[1,2-b]pyridazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
• Target: Anti-infection
• Target Protein: P0DTD1,P0C6X7,K9N7C7
• Solubility: Soluble in DMSO
• Appearance: Solid
• Storage: Dry, dark and at 2 - 8 °C for six months or -20°C for two years.
• Analysis method: HPLC
• IC50: EC50: 3.3 μM (SARS-CoV-2), 4.7 μM (SARS-CoV-2 alpha), 32 μM (SARS-CoV-2 beta), 3.7 μM (SARS-CoV-2 gamma) and 9.2 μM (SARS-CoV-2 delta)
• IUPAC Name: 2-ethylbutyl (2S)-2-[[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
• InChI: InChI=1S/C27H35N6O8P/c1-4-18(5-2)13-38-26(36)17(3)32-42(37,41-19-9-7-6-8-10-19)39-14-21-23(34)24(35)27(15-28,40-21)22-12-11-20-25(29)30-16-31-33(20)22/h6-12,16-18,21,23-24,34-35H,4-5,13-14H2,1-3H3,(H,32,37)(H2,29,30,31)/t17-,21+,23+,24+,27-,42-/m0/s1
• InChIKey: RWWYLEGWBNMMLJ-YSOARWBDSA-N
• SMILES: CCC(CC)COC(=O)[C@H](C)N[P@](=O)(OC[C@@H]1[C@H]([C@H]([C@](O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4

Remdesivir（Cat No.:I009001）is an antiviral medication used for the treatment of COVID-19 caused by the SARS-CoV-2 virus. It works by inhibiting the viral RNA-dependent RNA polymerase, an enzyme essential for viral replication. By interfering with viral RNA synthesis, Remdesivir reduces the ability of the virus to multiply, helping to control the infection. Administered intravenously, it is most effective when given early in the course of the disease. Remdesivir has been shown to shorten recovery time in hospitalized COVID-19 patients, offering a critical option in managing severe cases of the infection.