Remlarsen sodium

• CAT Number: I040116
• Molecular Weight: 17163.00
• Purity: ≥95%

Remlarsen sodium (Cat No.: I040116) is a synthetic antisense oligonucleotide that targets microRNA-29 (miR-29), a key regulator of extracellular matrix production and fibrosis. By inhibiting miR-29, Remlarsen upregulates the expression of collagen and other matrix proteins, promoting tissue remodeling and wound healing. It is primarily investigated for treating fibrotic skin disorders and improving surgical scar outcomes. Delivered locally, Remlarsen sodium helps modulate gene expression at the post-transcriptional level, offering a novel therapeutic strategy in regenerative medicine and fibrotic disease management.

Reference

[1]. Corrie L Gallant-Behm, et al. A MicroRNA-29 Mimic (Remlarsen) Represses Extracellular Matrix Expression and Fibroplasia in the Skin. J Invest Dermatol. 2019 May;139(5):1073-1081.
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